Staff Profile
Dr Laura Walker
Research Associate
- Address: Translational and Clinical Research Institute
Newcastle University Centre for Cancer
Faculty of Medical Sciences, Newcastle University
Framlington Place,
Newcastle upon Tyne,
NE2 4HH
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Background
Qualifications:
PhD in Molecular Biology - Newcastle University, 2023
MSci Biochemistry (Hons) - Newcastle University, 2019
Past positions:
AMLo Biosciences Ltd - Postdoctoral Research Associate, 2024-2025
Newcastle University - Postdoctoral Research Associate, 2022-2023
Publications
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Articles
- Sloan P, Husain A, Lye J, Best K, Walker L, Richardson G, Armstrong J, Lovat P. Utility of Combined Immunohistochemical Staining for AMBRA1 and Loricrin for Improving the Pathologic Diagnosis of High-Grade Dysplastic Nevi. American Journal of Dermatopathology 2026, 48(9), 691-697.
- Brittain N, Paschalis A, Nelson R, Adamson B, Walker L, Duncan R, Smith GR, McGill S, Burchmore RJ, Bogdan D, Jiménez-Vacas JM, Welti J, Yuan W, Robson CN, Rescigno P, Luzzi S, Sharp A, de Bono J, Gaughan L. Splicing factor TRA2B enhances synthesis of androgen receptor variant AR-V7 in prostate cancer cells. The Journal of Clinical Investigation 2026, 136(7), e198264.
- Booth LK, Redgrave RE, Camacho-Encina M, Trevisan-Herraz M, Walker L, Ma G, Mathison L, Tual-Chalot ST, Gill J, Korolchuk V, Richardson GD. Small molecule mitophagy enhancers prevent doxorubicin-induced cardiomyocyte senescence–therapeutic potential in anthracycline-induced cardiotoxicity?. Heart 2026, 112(Suppl 1), A260-A261.
- Paschalis A, Figueiredo I, Bogdan D, Lundberg A, Santos R, Gurel B, Taha T, Longoria O, Ferreira A, Bertan C, Brittain N, Nelson R, Walker L, Neeb A, Welti J, Yuan W, Mitsopoulos C, Plymate SR, Haffner MC, Sowalsky AG, Carreira S, Sharp A, Gaughan L, de Bono J. Androgen receptor splice variant 7 expression levels distinguish AR-mutated from nonmutated metastatic castration-resistant prostate cancers. The Journal of Clinical Investigation 2026, 136(7), e198193.
- Garnham R, Geh D, Nelson R, Ramon-Gil E, Wilson L, Schmidt EN, Walker L, Adamson B, Buskin A, Hepburn AC, Hodgson K, Kendall H, Frame FM, Maitland N, Coffey K, Strand DW, Robson CN, Elliott DJ, Heer R, Macauley M, Munkley J, Gaughan L, Leslie J, Scott E. ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (ST3Gal1) synthesis of Siglec ligands mediates anti-tumour immunity in prostate cancer. Communications Biology 2024, 7(1), 276.
- Walker L, Duncan R, Adamson B, Kendall H, Brittain N, Luzzi S, Jones D, Chaytor L, Peel S, Crafter C, O'Neill DJ, Gaughan L. Defining splicing factor requirements for androgen receptor variant synthesis in advanced prostate cancer. Molecular Cancer Research 2024, 22(12), 1128-1142.
- Adamson B, Brittain N, Walker L, Duncan R, Luzzi S, Rescigno P, Smith GR, McGill S, Burchmore RJS, Willmore E, Hickson I, Robson CN, Bogdan D, Jimenez-Vacas JM, Paschalis A, Welti J, Yuan W, McCracken SR, Heer R, Sharp A, de Bono J, Gaughan L. The catalytic subunit of DNA-PK regulates transcription and splicing of AR in advanced prostate cancer. Journal of Clinical Investigation 2023, 133(22), e169200.