Staff Profile
Dr Holly Fisher
Biostatistician (Senior Research Associate)
- Email: holly.fisher@ncl.ac.uk
- Address: Population Health Sciences Institute
Faculty of Medical Sciences
Newcastle University
Background
Overview
I am a biostatistician (research associate) based in the Population Health Sciences Institute working on a number of clinical trials and observational studies. I am a member of the PHSI Biostatistics Research Group.
Previous positions
- Research associate in Statistical Genetics, Institute of Genetic Medicine, Newcastle University
Qualifications
- PhD, Newcastle University (2009 - 2013)
- MMathStat, Newcastle University (2005 - 2009)
Publications
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Articles
- Grixti L, Fisher H, Priestley J, McMullan C, Woollven A, Perros P, Mitchell AL, Gan EH, Pearce SH. Prevalence and severity of fatigue in treated hypothyroidism: results of a UK survey. European Thyroid Journal 2025, 14(3).
- Pippard BJ, Neal MA, Holland CW, Maunder AM, Forrest I, Lawson RA, Fisher HF, Matthews JNS, Wild JM, Simpson AJ, Thelwall PE. Assessing Lung Ventilation and Bronchodilator Response in Asthma and Chronic Obstructive Pulmonary Disease with 19F-MRI. Radiology 2024, 313(3).
- Gravestock P, Clark E, Morton M, Sharma S, Fisher H, Walker J, Wood R, Hancock H, Waugh N, Cooper A, Maier R, Marshall J, Chandler R, Bahl A, Crabb S, Jain S, Pedley I, Jones R, Staffurth J, Heer R. Using the AR-V7 biomarker to determine treatment in metastatic castrate resistant prostate cancer, a feasibility randomised control trial, conclusions from the VARIANT trial. NIHR Open Research 2023, 2, 49.
- Nugent M, Bryant V, Butcher C, Fisher H, Gill S, Goranova R, Hiu S, Lindley L, O'Hara J, Oluboyede Y, Patterson J, Rapley T, Robinson T, Rousseau N, Ryan V, Shanmugasundaram R, Sharp L, Smith Whelan R, Stocken DD, Ternent L, Wilson JA, Walker J. Photobiomodulation in the management of oral mucositis for adult head and neck cancer patients receiving irradiation: the LiTEFORM RCT. Health Technology Assessment 2022, 26(46).
- O'Hara J, Hayes L, Fisher H, Wilson JA. 'Persistent Throat Symptoms' versus 'Laryngopharyngeal Reflux' – a cross sectional study refining the clinical condition. BMJ Open Gastroenterology 2022, 9(1), e000850.
- Fisher HF, Boys RJ, Gillespie CS, Proctor CJ, Golightly A. Parameter inference for a stochastic kinetic model of expanded polyglutamine proteins. Biometrics 2022, 78(3), 1195-1208.
- Mowbray C, Tan A, Vallee M, Fisher H, Chadwick T, Brennand C, Walton KE, Pickard RS, Harding C, Aldridge PA, Hall J. Multidrug-resistant Uro-associated Escherichia coli Populations and Recurrent Urinary Tract Infections in Patients Performing Clean Intermittent Self-catheterisation. European Urology Open Science 2022, 37, 90-98.
- Murillo Perez CF, Fisher H, Hiu S, Kareithi DK, Adekunle F, Mayne T, Malecha E, Ness E, van der Meer DJ, Lammers WJ, Trivedi PJ, Battezzati PM, Nevens F, Kowdley KV, Bruns T, Cazzagon N, Floreani A, Mason AL, Parés A, Londoño M-C, Invernizzi P, Carbone M, Lleo A, Mayo MJ, Dalekos GN, Gatselis NK, Thorburn D, Verhelst X, Gulamhusein A, Janssen HLA, Smith R, Flack S, Mulcahy V, Trauner M, Bowlus CL, Lindor KD, Corpechot C, Jones D, Mells G, Hirschfield GM, Wason J, Hansen BE. Greater Transplant-Free Survival in Patients Receiving Obeticholic Acid for Primary Biliary Cholangitis in a Clinical Trial Setting Compared to Real-World External Controls. Gastroenterology 2022, 163(6), 1630-1642.e3.
- Welk B, Fisher H, Chadwick T, Harding C. Efficacy of antibiotic prophylaxis among intermittent catheter users with different neurologic diseases: A secondary analysis of the AnTIC Trial. Continence 2022, 1, 100004.
- Pippard BJ, Neal MA, Maunder AM, Hollingsworth KG, Biancardi A, Lawson RA, Fisher H, Matthews JNS, Simpson AJ, Wild JM, Thelwall PE. Reproducibility of 19F-MR ventilation imaging in healthy volunteers. Magnetic Resonance in Medicine 2021, 85(6), 3343-3352.
- Hegade VS, Mells GF, Fisher H, Kendrick S, DiBello J, Gilchrist K, Alexander GJ, Hirschfield GM, Sandford RN, Jones DEJ. Pruritus Is Common and Undertreated in Patients With Primary Biliary Cholangitis in the United Kingdom. Clinical Gastroenterology and Hepatology 2019, 17(7), 1379-1387.e3.
- Clark E, Morton M, Sharma S, Fisher H, Howel D, Walker J, Wood R, Hancock H, Maier R, Marshall J, Bahl A, Crabb S, Jain S, Pedley I, Jones R, Staffurth J, Heer R. Prostate cancer androgen receptor splice variant 7 biomarker study - A multicentre randomised feasibility trial of biomarker-guided personalised treatment in patients with advanced prostate cancer (the VARIANT trial) study protocol. BMJ Open 2019, 9(12), e034708.
- Alblooshi H, Al Safar H, Fisher HF, Cordell HJ, El Kashef A, Al Ghaferi H, Shawky M, Reece S, Hulse GK, Tay GK. A case-control genome wide association study of substance use disorder (SUD) identifies novel variants on chromosome 7p14.1 in patients from the United Arab Emirates (UAE). American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics 2019, 180(1), 68-79.
- Wong LL, Fisher HF, Stocken DD, Rice S, Khanna A, Heneghan MA, Oo YH, Mells G, Kendrick S, Dyson JK, Jones DEJ. The Impact of Autoimmune Hepatitis and Its Treatment on Health Utility. Hepatology 2018, 68(4), 1487-1497.
- McClurg D, Walker K, Pickard R, Hilton P, Ainsworth H, Leonard K, Suresh S, Nilsson A, Gillespie N. Participant experiences of clean intermittent self-catheterisation, urinary tract infections and antibiotic use on the ANTIC trial – A qualitative study. International Journal of Nursing Studies 2018, 81, 1-7.
- Paleri V, Sawant R, Mehanna H, Ainsworth H, Stocken D. Laryngeal dysplasia and narrow band imaging: Secondary analysis of published data supports the role in patient follow-up. Clinical Otolaryngology 2018, 43(6), 1439-1442.
- Pickard RS, Chadwick T, Oluboyede Y, Brennand C, von Willamowitz-Moellendorff A, McClurg D, Wilkinson J, Ternent L, Ainsworth H, Walton K, McColl E, Vale L, Wood R, Abdel-Fattah M, Hilton P, Fader M, Harrison S, Larcombe J, Little P, Timoney A, N'Dow J, Armstrong H, Morris N, Walker K, Thiruchelvam N. Continuous low-dose antibiotic prophylaxis to prevent urinary tract infection in adults who perform clean intermittent self-catheterisation: the AnTIC RCT. Health Technology Assessment 2018, 22(24), i-102.
- Fisher H, Oluboyede Y, Chadwick T, Abdel-Fattah M, Brennand C, Fader M, Harrison S, Hilton P, Larcombe J, Little P, McClurg D, McColl E, Ndow J, Ternent L, Timoney A, Vale L, Thiruchelvam N, von Wilamowitz-Moellendorff A, Wilkinson J, Walton K, Wood R, Pickard RS. Continuous low-dose antibiotic prophylaxis for adults with repeated urinary tract infections (AnTIC): a randomised, open-label trial. The Lancet Infectious Diseases 2018, 18(9), 957-968.
- Boys RJ, Ainsworth HF, Gillespie CS. Bayesian inference for a partially observed birth-death process using data on proportions. Australian and New Zealand Journal of Statistics 2018, 60(2), 157-173.
- Soomro N, Lecouturier J, Stocken DD, Shen J, Hynes AM, Ainsworth HF, Breen D, Oades G, Rix D, Aitchison M. Surveillance versus ablation for incidentally diagnosed small renal tumours: The SURAB feasibility RCT. Health Technology Assessment 2017, 21(81), 1-68.
- Ainsworth HF, Shin S-Y, Cordell HJ. A comparison of methods for inferring causal relationships between genotype and phenotype using additional biological measurements. Genetic Epidemiology 2017, 41(7), 577-586.
- Pazderska A, Oftedal BE, Napier CM, Ainsworth HF, Husebye ES, Cordell HJ, Pearce SHS, Mitchell AL. A Variant in the BACH2 Gene Is Associated With Susceptibility to Autoimmune Addison's Disease in Humans. Journal of Clinical Endocrinology and Metabolism 2016, 101(11), 3865-3869.
- Ainsworth HE, Unwin J, Jamison DL, Cordell HJ. Investigation of Maternal Effects, Maternal-Fetal Interactions and Parent-of-Origin Effects (Imprinting), Using Mothers and Their Offspring. Genetic Epidemiology 2011, 35(1), 19-45.
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Conference Proceedings (inc. Abstracts)
- Holland C, Neal M, Pippard B, Forrest I, Lawson R, Fisher HF, Matthews JN, Hollingsworth KG, Simpson AJ, Wild J, Thelwall PE. Comparison of 19F-MRI, CT and spirometry in a patient with airways disease. In: European Respiratory Society International Congress. 2022, Barcelona, Spain: European Respiratory Society.
- Holland C, Neal M, Pippard B, Forrest I, Burns G, Sabroe I, Lawson R, Fisher H, Matthews JNS, Simpson AJ, Wild J, Thelwall P. Assessing pulmonary ventilation and treatment response in patients with asthma and COPD using 19F-MRI: results from the LIFT study. In: British Thoracic Society Winter Meeting 2022. 2022, London, UK: Thorax.
- Neal M, Pippard B, Forrest I, Lawson R, Fisher HF, Matthews JNS, Hollingsworth K, Simpson AJ, Wild J, Thelwall P. 19F-MRI of inhaled perfluoropropane in patients with asthma and patients with COPD pre- and post-bronchodilator therapy. In: International Society for Magnetic Resonance in Medicine Annual Meeting & Exhibition. 2021, Virtual.
- Ainsworth HF, Cordell HJ. Using gene expression data to identify causal pathways between genotype and phenotype in a complex disease: Application to Genetic Analysis Workshop 19. In: Genetic Analysis Workshop 19: Sequence, Blood Pressure and Expression Data. 2016, Vienna, Austria: BioMed Central Ltd.
- Ainsworth HF, Shin SY, Cordell HJ. A comparison of methods for inferring causal relationships between genotype and phenotype using multi-omics data. In: 2015 Annual Meeting of the International Genetic Epidemiology Society. 2015, Baltimore, MD, USA: Wiley-Blackwell Publishing Ltd.
- Cordell HJ, Ainsworth HF, Unwin J. Investigation of maternal effects, maternal-foetal interactions and parent-of-origin effects (imprinting), using mothers and their offspring. In: 18th Annual Meeting of the International Genetic Epidemiology Society. 2009, Oahu, Hawaii: Genetic Epidemiology: John Wiley & Sons, Inc.